Solution equilibria of the cytosine- and guanine-rich sequences near the promoter region of the n-myc gene which contain stable hairpins within lateral loops
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چکیده
Solution equilibria of the cytosineand guanine-rich sequences near the promoter region of the n-myc gene which contain stable hairpins within lateral loops Sanae Benabou, Rubén Ferreira, Anna Aviñó, Carlos González, Ramon Eritja, Joaquim Jaumot, Raimundo Gargallo 1. Solution Equilibria and Chemometrics group (Associate Unit UB-CSIC), Department of Analytical Chemistry, University of Barcelona, Diagonal 645, E-08028 Barcelona, Spain 2. Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), CIBER-BBN Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Jordi Girona 18-26, E-08034 Barcelona, Spain 3. Institute of Physical Chemistry “Rocasolano”, CSIC, Serrano 119, E-28006 Madrid, Spain
منابع مشابه
Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops.
BACKGROUND Cytosine- and guanine-rich regions of DNA are capable of forming complex structures named i-motifs and G-quadruplexes, respectively. In the present study the solution equilibria at nearly physiological conditions of a 34-base long cytosine-rich sequence and its complementary guanine-rich strand corresponding to the first intron of the n-myc gene were studied. Both sequences, not yet ...
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